Biology – Page 13
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ResearchFreeze–thaw cycles could explain how ancient RNA replicated without enzymes
Discovery solves puzzle of RNA world hypothesis
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FeatureLife’s chemistry goes through the looking glass
Chemists were taught that natural systems only use L-amino acids. Andy Extance finds out just how wrong that is proving
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NewsChemistry Nobel laureate Sidney Altman dies at 82
Canadian–American molecular biologist won the 1989 prize for discovering RNA’s catalytic ability
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FeatureA decade of CAR-T cell therapy
Nina Notman looks at the revolutionary treatment already taking on cancer, now aiming for wider use
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ArticleNanotechnology for a healthier, cleaner world for all
Using novel polymer fluorophores to study, detect and treat life-threatening diseases
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ResearchSea sponges own unique chemistry goes beyond that of their bacterial guests
Biologically potent compounds can be made by sea sponges themselves
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ArticleCausal emergence might explain how living systems can operate
Life does not run like clockwork
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BusinessPatent office cements priority for Crispr gene editing in cells
Nobel laureates’ failed challenge means companies may need extra patent licenses
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FeatureThe curious case of the ancient brain
A 2000 year old decapitated Yorkshire man and the ancient proteins in his preserved brain might provide clues to modern diseases, as Hayley Bennett discovers
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BusinessModerna sued over Covid-19 vaccine-related patents
Arbutus and Genevant say lipid nanoparticles that protect mRNA infringe six key patents
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ResearchEpigenetic MRI offers a way to understand how the brain learns
First tests in humans could be as little as year away, researchers claim
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ResearchReprogrammed bacterium turns carbon dioxide into chemicals on industrial scale
Process achieved at industrial scale in 120 litre reactor
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ResearchElectric field of ATP synthase suggests enzyme has functions beyond catalysis
Study links energy-making enzyme with proton migration in ATP formation, and reinforces predictions that its catalytic efficiency is around 90%
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FeatureSequencing one cell at a time
New advances that allow scientists to uncover the molecular differences between individual cells could revolutionise medicine, Ian le Guillou finds
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ResearchBiochemical secrets of tarantula’s painful bite could point to perfect painkillers
King baboon spider venom could help scientists develop potent analgesics
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ResearchNew microscope makes tracking chiral molecules in live cells possible
The instrument uses circularly polarised light to tell left- and right-handed species apart and monitor them in space and time
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ResearchLeft-handed nanoparticles are far better vaccine adjuvants than their mirror images
Chiral gold nanoparticles shown for the first time to elicit differing immune responses in cells and live mice
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OpinionThe shadow of drug resistance
Why do some medicines stop working, and can we avoid it for Covid-19 antivirals?
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ResearchEngineered enzyme speeds up sedate organic reaction
Biochemical optimisation applied to the Morita–Hillman–Baylis reaction
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ResearchEvolved enzymes carry out new-to-nature radical chemistry
Directed evolution produces enzymes that can ‘tame’ radical intermediates for asymmetric catalytic reactions